Dr Jean-Marie Peron
Faculties, deparments and locations
- Faculty of Health, Science, Social Care and Education
- Department of Chemical and Pharmaceutical Sciences
- School of Life Sciences, Pharmacy and Chemistry
- Penrhyn Road
Senior Lecturer in Organic and Pharmaceutical Chemistry
- Email:
- jm.peron@kingston.ac.uk
About
In 2021, I completed my PhD in medicinal chemistry under Prof. R C. Hider, King's College London. After a few short research assignments, in 2002 I joined Prof. Keith Jones' group at Kingston University as a research fellow. During that time, I worked on semi-synthetic cardioactive steroids (bufadienolides); on a project funded by the Special Trustees of St Thomas' Hospital. In 2006, I changed direction and took on the role of NMR senior technician at Kingston, supporting teaching and research in the School of LSPC. During that time I collaborated with a number of academic colleagues offering NMR expertise to help answer varied scientific questions. In December 2017, I returned to the Department of Chemical and Pharmaceutical Sciences as lecturer in organic and pharmaceutical chemistry. I am now senior lecturer, and since June 2023 I have been the course leader for the undergraduate Chemistry programme.
Qualifications
- D.U.T. de Chimie: I.U.T. de Chimie, Université de Rennes 1, France, 1993
- BSc (Hons.) Chemistry: Kingston University, UK, 1995
- PhD Medicinal Chemistry: King's College London, UK, 2002
- Fellowship of the Higher Education Academy (FHEA), 2019
Domains
Senior Lecturer:
I teach chemistry on a number of courses. Although my role is to teach organic and pharmaceutical chemistry at levels 4-7, I also teach general chemistry to level 4 life sciences students (LS4002) and NMR and spectroscopy data analysis and interpretation to level 5 pharmaceutical science students (CH5007). I lead two modules: CH4005 - Foundation Chemistry and CH7070 - Design, Discovery and Development of Pharmaceuticals. I am involved in supervising a 1 MPharm, 7 MSc and 4 BSc projects during the academic year. I also am the personal tutor for up to 24 students in the Department of Chemical and Pharmaceutical Sciences.
Course Leader for Chemistry (June 2023 - current):
I am the Course Leader for the undergraduate Chemistry programmes (F100, F123). My experience as Admissions Tutor has given me clear insights into the recruitment processes for the two interlinked courses. This will inform my role as Chemistry CL, as we move forward and implement changes, such as embedding KU's Future Skills scheme, in the chemistry course.
Admissions Tutor for Chemistry and Pharmaceutical Science (Sept. 2020 - June 2023):
I was responsible for reviewing a number of applications to undergraduate courses in Chemistry and Pharmaceutical Sciences, working in close collaboration with the Faculty Admissions Team and the Faculty Recruitment Team. A key aspect of my role involved facilitating clearing and admissions activities in the Department of Chemical and Pharmaceutical Sciences and ensuring academic colleagues were equipped for clearing.
Qualifications
- Fellow of the Higher Education Academy (FHEA)
Course director
Courses taught
My current research interests include the structure elucidation of naturally occurring bioactive compounds (RMM<800DA) using high-resolution FT-NMR spectroscopy, and organic synthesis to prepare molecules with medicinal properties. I also collaborate on a number of projects where solution phase NMR is used as a means to quantify drugs (e.g. in formulation studies), their metabolites or investigate drug stability (e.g. anticancer drug cocktails). My interest is not limited to organic-type chemistry, I am also keen to collaborate on materials chemistry projects. I currently supervise and co-supervise PhD and MRes students in three different fields: NMR research, cancer research and chemical synthesis of metal chelators for sensing.
Up-to-date publication list available here: https://bit.ly/4a87p8o (MS Word Document).
Specialisms
- Synthetic Organic Chemistry
- Natural Products Structure Elucidation
- Bruker Avance III NMR Spectrometer Automation and Topspin 3+ AU Programming
- NMR Data Processing and Interpretation
Sept. 2023 - current: Member of the RSC Directors of Undergraduate Teaching policy group.
Professional and scholarly affiliations
- Member of the Royal Society of Chemistry (MRSC), 2014
- Fellowship of the Higher Education Academy (FHEA), 2019
Publications
Modified PSYCHE NMR - the possibility for the direct semi-quantitation of components in mixtures
Durrant, Arija, Peron, Jean-Marie R., Langat, Moses K., Robertson, Cameron and Le Gresley, Adam, 2024, Talanta (268), 1, pp 125332
In situ formation of low molecular weight organogelators for slick solidification
Peron, Jean-Marie R., Packman, Hollie, Peveler, William J. and Bear, Joseph C., 2020, RSC Advances (10), 23, pp 13369-13373
Application of pure shift and diffusion NMR for the characterisation of crude and processed pyrolysis oil
Le Gresley, Adam, Broadberry, Grace, Robertson, Cameron, Peron, Jean-Marie, Robinson, Joshua and O'Leary, Shane, 2019, Journal of Analytical and Applied Pyrolysis (140), pp 281-289
[sup]1H NMR quantification of spray dried and spray freeze-dried saccharide carriers in dry powder inhaler formulations
Babenko, Mai, Peron, Jean-Marie R., Kaialy, Waseem, Calabrese, Gianpiero, Alany, Raid G. and ElShaer, Amr, 2019, International Journal of Pharmaceutics (564), pp 318-328
A semi-automatic approach to the characterisation of dark chocolate by Nuclear Magnetic Resonance and multivariate analysis
Le Gresley, Adam and Peron, Jean-Marie R., 2019, Food Chemistry (275), pp 385-389
Salman, D, Peron, J-M R, Goronga, T, Barton, S, Swinden, J and Nabhani-Gebara, Shereen, 2016, Annales Pharmaceutiques Francaises (74), 2, pp 119-128
Evaluation of the stability profile of anticancer drugs: a review of Ifosfamide and Mesna regimen for the treatment of metastatic soft tissue sarcoma
Salman, Dahlia, Swinden, Julian, Barton, Stephen, Peron, Jean-Marie and Nabhani-Gebara, Shereen, 2016, Journal of Oncology Pharmacy Practice (22), 1, pp 86-91
New investigations into the stability of Mesna using LC-MS/MS and NMR
Salman, Dahlia, Swinden, Julian, Peron, Jean-Marie R., Barton, Stephen and Nabhani-Gebara, Shereen, 2016, Expert review of anticancer therapy (16), 1, pp 123-130
Improving drug stability to promote home cancer therapy
Salman, Dahlia, Swinden, Julian, Barton, Stephen, Peron, Jean-Marie R. and Nabhani-Gebara, Shereen, 2014, Hospital Pharmacy Europe, 72, pp 38-40
Selective inhibition of the cellular sodium pump by emicymarin and 14ss anhydroxy bufadienolides
Hilton, Philip, McKinnon, William, Gravett, Edward, Peron, Jean-Marie, Frampton, Christopher M, Nicholls, M Gary and Lord, Gwyn, 2010, Steroids (75), 13-14, pp 1137-1145
Elevation of anions in exercise-induced acidosis: a study by ion-exchange chromatography/mass spectrometry
McKinnon, William, Pentecost, C, Lord, Gwyn A, Forni, Lui G, Peron, Jean-Marie and Hilton, Philip J, 2008, Biomedical Chromatography (22), 3, pp 301-305
Unexplained acidosis of malnutrition: a study by ion-exchange chromatography/mass spectrometry
Hilton, P.J., McKinnon, W., Lord, G.A., Peron, J.-M.R. and Forni, L.G., 2006, Biomedical Chromatography (20), 12, pp 1386-1389
A rapid LC-MS method for determination of plasma anion profiles of acidotic patients
McKinnon, William, Lord, Gwyn A, Forni, Lui G, Peron, Jean-Marie R and Hilton, Philip J, 2006, Journal of Chromatography B (833), 2, pp 179-185
Synthesis and anthelmintic properties of arylquinolines with activity against drug-resistant nematodes
Rossiter, Sharon, Peron, Jean-Marie, Whitfield, Philip J. and Jones, Keith, 2005, (15), 21, pp 4806-4808
Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis
Forni, Lui G, McKinnon, William, Lord, Gwyn A, Treacher, David F, Peron, Jean-Marie R and Hilton, Philip J, 2005, Critical Care (Online) (9), 5, pp R591-R595
P-440: Differential inhibition of Na-K ATPases by synthetic 14 [beta] bufadienolides
Hilton, Philip J., McKinnon, W., Jones, Keith, Peron, Jean-Marie, Gravett, Edward C. and Lord, Gwyn A, 2005, American Journal of Hypertension (18), 5, pp 166A-166A
A new route to 5-aryl and 5-heteroaryl-2-pyrones via Suzuki coupling of a 2-pyrone-5-boronate ester
Gravett, Edward C., Hilton, Philip J, Jones, Keith and Peron, Jean-Marie, 2003, Synlett (2), pp 0253-0255
Quantification and identification of compounds by qNMR and a quantitative PSYCHE NMR method
Durrant, Arija, Peron, Jean-Marie R, Le Gresley, Adam and Langat, Moses K(2023). In: The 19th European Nuclear Magnetic Resonsance Congress (EuroMar 2023), 9-13 July 2023 :Glasgow, U.K.
Identification and quantification of isolated medicinal compounds by PSYCHE NMR and DOSY NMR
Durrant, Arija, Peron, Jean-Marie, Le Gresley, Adam and Langat, Moses(2022). In: Ampere NMR School 2022, 19-25 Jun 2022 :Zakopane, Poland
Ambulatory chemotherapy: the bench to bedside
Salman, Dahlia, Barton, Stephen, Swinden, Julian, Peron, Jean-Marie, Wertheim, David, Kayyali, Reem and Nabhani-Gebara, Shereen(2015). In: Quality Improvement in Chemotherapy Commissioning Meeting, 10 Feb 2015 :London, U.K.
The potential of NMR in oncology pharmacy: a forced degradation study of Ifosfamide
Salman, D., Peron, J.M., Goronga, T., Swinden, J., Barton, S. and Nabhani-Gebara, S.(2014). In: UKPharmasci APS Conference 2014, 10-12 Sep 2014 :Hatfield, U.K.
Evaluation of the stability of Ifosfamide and Mesna in elastomeric pumps : bench to bedside
Salman, Dahlia, Swinden, Julian, Barton, Stephen, Peron, Jean-Marie and Nabhani-Gebara, Shereen(2014). In: XIV International Symposium on Oncology Pharmacy Practice (ISOPP XIV) : Building Partnerships in Care, 02 - 05 Apr 2014 :Montreal, Canada
Evaluation of the solubility and stability of ifosfamide in order to answer practice based challenges
Salman, Dahlia, Swinden, Julian, Peron, Jean-Marie, Barton, Stephen and Nabhani-Gebara, Shereen(2013). In: 16th Annual BOPA Symposium, 18 - 20 Oct 2013 :Edinburgh, U.K.
Optimising home chemotherapy through analytical research : the physicochemical stability of Mesna using LC-MS/MS and NMR
Salman, Dahlia, Swinden, Julian, Peron, Jean-Marie, Barton, Stephen and Nabhani-Gebara, Shereen(2013). In: UKPharmasci APS Conference 2013, 02 - 04 Sep 2013 :Edinburgh, U.K.
Optimization and uncertainty budgets of externally standardised NMR assays
Fardus, Fahmina, Warren, John, Le Gresley, Adam and Peron, Jean-Marie(2011). In: Bruker MR Users' Meeting 2011, 15-16t Nov 2011 :Coventry, UK
Gallery of work
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2020 RSC Organic Division, London and South East Regional Meeting
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2020 RSC Organic Division, London and South East Regional Meeting
Speakers and organising committee
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Arija Durrant and her poster at NMR Ampere Conference 2022, Poland
Arija presented her recent work on PSYCHE NMR (a pure shift NMR technique) as a quantitative 1H NMR technique.
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Arija Durrant and her poster at EuroMar 2023, UK
Arija presented an update of her PhD work on PSYCHE NMR as a semi-quantitative 1H NMR technique.
