Professor Mark Fielder
Faculties, deparments and locations
- Faculty of Health, Science, Social Care and Education
- Department of Biomolecular Sciences
- School of Life Sciences, Pharmacy and Chemistry
- Penrhyn Road
Professor of Medical Microbiology
- Email:
- m.fielder@kingston.ac.uk
About
I was awarded a PhD in Microbiology and Immunology from Kings College London in 1995 winning the Tadion-Rideal Prize for outstanding postgraduate work. I then undertook Postdoctoral position at St Georges Hospital London on mucosal vaccination against Vibrio cholerae. After joining Kingston University as a lecturer (1998) in medical Microbiology and awarded a chair in Medical Microbiology in 2011. I act as an advisor for the Clinical Laboratory Sciences Institute (Veterinary antimicrobial susceptibility testing) and sit on the Parliamentary and Scientific committee. My research team are multidisciplinary working on rapid detection systems for infectious disease diagnosis and to overcome antimicrobial resistance in clinical and veterinary settings and looking at antibiotic overspill into wild raptors. I am currently the President of the Society for Applied Microbiology
Qualifications
- PGCTLHE/FHEA
- Tadion-Rideal Prize for outstanding Doctoral Work, Kings College London
- PhD, Kings College London
- BSc Microbiology, Kings College London
Domains
My research group has a generally broad scope but all under the one health banner. We are involved in trying to understand how bacteria mutate in the face of different selective pressures as a result of antibiotic pressure. We are looking at the discovery of novel antibiotics from different environmental niches and we are looking at the development of novel and rapid diagnostics that can be used in both human and animal health to facilitate early identification of pathogens and so appropriate and targeted treatment with anti-infectives. This approach also helps in the stewardship and protection of antibiotics. We are looking at antibiotic resistance spillover into wild raptor populations with the Sussex Peregrine Study Group.
We are also working with the veterinary and farming communities to understand antimicrobial resistance using both traditional laboratory science as well as social science to understand the publics perception of antibiotic use and benefits.
Publications
Willingness of the UK public to volunteer for testing in relation to the COVID-19 pandemic
Vandrevala, Tushna, Montague, Amy, Terry, Philip and Fielder, Mark D., 2022, BMC Public Health (22), pp 565
Wild animal and zoonotic disease risk management and regulation in China : examining gaps and One Health opportunities in scope, mandates, and monitoring systems
Li, Hongying, Chen, Yufei, Machalaba, Catherine C., Tang, Hao, Chmura, Aleksei A., Fielder, Mark D. and Daszak, Peter, 2021, One Health (13), pp 100301
Knowledge, attitude, and practice regarding zoonotic risk in wildlife trade, southern China.
Li, Hongying, Daszak, Francesca, Chmura, Aleksei, Zhang, Yunzhi, Terry, Philip and Fielder, Mark, 2021, EcoHealth (18), 1, pp 95-106
Determination of metabolic activity in planktonic and biofilm cells of Mycoplasma fermentans and Mycoplasma pneumoniae by nuclear magnetic resonance
Awadh, Ammar A., Le Gresley, Adam, Forster-Wilkins, Gary, Kelly, Alison F. and Fielder, Mark D., 2021, Scientific Reports (11), pp 5650
Visualisation and biovolume quantification in the characterisation of biofilm formation in 'Mycoplasma fermentans'
Awadh, Ammar A., Kelly, Alison F., Forster-Wilkins, Gary, Wertheim, David, Giddens, Richard, Gould, Simon W. and Fielder, Mark D., 2021, Scientific Reports (11), pp 11259
Nipah virus dynamics in bats and implications for spillover to humans
Epstein, Jonathan H., Anthony, Simon J., Islam, Ariful, Kilpatrick, A. Marm, Ali Khan, Shahneaz, Balkey, Maria D., Ross, Noam, Smith, Ina, Zambrana-Torrelio, Carlos, Tao, Yun, Islam, Ausraful, Quan, Phenix Lan, Olival, Kevin J., Khan, M Salah Uddin, Gurley, Emily S., Hossein, M Jahangir, Field, Hume E., Fielder, Mark D., Briese, Thomas, Rahman, Mahmudur, Broder, Christopher C., Crameri, Gary, Wang, Lin-Fa, Luby, Stephen P., Lipkin, W. Ian and Daszak, Peter, 2020, Proceedings of the National Academy of Sciences of the United States of America (117), 46, pp 29190-29201
Human-animal interactions and bat coronavirus spillover potential among rural residents in Southern China
Li, Hongying, Mendelsohn, Emma, Zong, Chen, Zhang, Wei, Hagan, Emily, Wang, Ning, Li, Shiyue, Yan, Hong, Huang, Huimin, Zhu, Guangjian, Ross, Noam, Chmura, Aleksei, Terry, Philip, Fielder, Mark, Miller, Maureen, Shi, Zhengli and Daszak, Peter, 2019, Biosafety and Health (1), 2, pp 84-90
Synthetic scale-up of a novel fluorescent probe and its biological evaluation for surface detection of 'Staphylococcus aureus'
Bywaters, Luke, Mulcahy-Ryan, Lauren, Fielder, Mark, Sinclair, Alex and Le Gresley, Adam, 2017, Molecular and Cellular Probes (36), pp 1-9
Heat treatment enhances the plant phenolic (+)-catechin, a weak antimicrobial agent when combined with copper sulphate
Holloway, A. C., Mueller-Harvey, I., Gould, S. W. J., Fielder, M. D., Naughton, D. P. and Kelly, A. P., 2015, Letters in Applied Microbiology (61), 4, pp 381-389
Identification of a novel plasmid-associated spectinomycin adenyltransferase gene spd in methicillin-resistant 'Staphylococcus aureus' ST398 isolated from animal and human sources
Jamrozy, Dorota, Coldham, Nicholas, Butaye, Patrick and Fielder, Mark, 2014, Journal of Antimicrobial Chemotherapy (69), 5, pp 1193-1196
Carriage of 'Staphylococcus' species in the veterinary visiting dog population in mainland UK : molecular characterisation of resistance and virulence
Wedley, Amy L, Dawson, Susan, Maddox, Thomas W, Coyne, Karen P, Pinchbeck, Gina L, Clegg, Peter, Jamrozy, Dorota, Fielder, Mark D., Donovan, David, Nuttall, Tim and Williams, Nicola J, 2014, Veterinary Microbiology (170), 1-2, pp 81-88
Complete Sequence of pSAM7, an IncX4 Plasmid Carrying a Novel bla[sub]CTX-M-14b Transposition Unit Isolated from ' Escherichia coli ' and ' Enterobacter cloacae ' from cattle
Stokes, M.O., AbuOun, M., Umur, S., Wu, G., Partridge, S. R., Mevius, D. J., Coldham, N. G. and Fielder, M. D., 2013, Antimicrobial Agents and Chemotherapy (57), 9, pp 4590-4594
Development of an in situ culture-free screening test for the rapid detection of Staphylococcus aureus within healthcare environments.
Sinclair, Alex, Mulcahy, Lauren, Geldeard, Lynsey, Malik, Samerah, Fielder, Mark and Le Gresley, Adam, 2013, (11), 20, pp 3307-3313
High throughput phenotypic analysis of 'Mycobacterium tuberculosis' and 'Mycobacterium bovis' strains' metabolism using Biolog Phenotype Microarrays
Khatri, Bhagwati, Fielder, Mark, Jones, Gareth, Newell, William, Abu-Oun, Manal and Wheeler, Paul.R., 2013, PLOS ONE (8), 1, pp e52673
Duration of maternal antibodies against canine distemper virus and hendra virus in pteropid bats
Epstein, Jonathan H, Baker, Michelle L, Zambrana-Torrelio, Carlos, Middleton, Deborah, Barr, Jennifer A, Dubovi, Edward, Boyd, Victoria, Pope, Brian, Todd, Shawn, Crameri, Gary, Walsh, Allyson, Pelican, Katey, Fielder, Mark D, Davies, Angela J, Wang, Lin-Fa and Daszak, Peter, 2013, PloS One (8), 6, pp e67584
The effect of copper(ii), iron(ii) sulphate, and vitamin C combinations on the weak antimicrobial activity of (+)-catechin against Staphylococcus aureus and other microbes
Holloway, Andrew, Mueller-Harvey, Irene, Gould, Simon W. G., Fielder, Mark D., Naughton, Declan P. and Kelly, Alison F., 2012, Metallomics : integrated biometal science (4), 12, pp 1280-1286
Comparative genotypic and phenotypic characterisation of methicillin-resistant staphylococcus aureus ST398 isolated from animals and humans
Jamrozy, Dorota M., Fielder, Mark D., Butaye, Patrick, Coldham, Nick G. and , 2012, PLoS ONE (7), 7, pp e40458
Detection and characterization of pCT-like plasmid vectors for blaCTX-M-14 in Escherichia coli isolates from humans, turkeys and cattle in England and Wales
Stokes, M. O., Cottell, J. L., Piddock, L. J. V., Wu, G., Wootton, M., Mevius, D. J., Randall, L. P., Teale, C. J., Fielder, M. D. and Coldham, N. G., 2012, Journal of Antimicrobial Chemotherapy (67), 7, pp 1639-1644
Identification and quantification of the antimicrobial components of a citrus essential oil vapor
Phillips, C.A., Gkatzionis, K., Laird, K., Score, J., Kant, A. and Fielder, M.D., 2012, Natural Product Communications (7), 1, pp 103-107
Sequence features contributing to chromosomal rearrangements in 'Neisseria gonorrhoeae'
Spencer-Smith, Russell, Varkey, Eldho, Fielder, Mark and Snyder, Lori, 2012, PLOS One (7), 9, pp e46023
The application of high resolution diffusion NMR to the analysis of manuka honey
Gresley, Adam le, Kenny, Jackie, Cassar, Claire, Kelly, Alison, Sinclair, Alex and Fielder, Mark D, 2012, Food Chemistry (135), 4, pp 2879-86
Enhancement of antimicrobial activities of whole and sub-fractionated white tea by addition of copper (II) sulphate and vitamin C against 'Staphylococcus aureus'; a mechanistic approach.
Holloway, Andrew C., Gould, Simon W. J., Fielder, Mark D., Naughton, Declan P. and Kelly, Alison F, 2011, BMC Complementary and Alternative Medicine (11), 1, pp 115
Effects of chelating agent and environmental stresses on microbial biofilms: relevance to clinical microbiology.
Al-Azemi, Ahmed, Fielder, Mark D, Abuknesha, Ramadan A. and Price, Robert G., 2011, Journal Of Applied Microbiology (110), 5, pp 1307-1313
Cattle, weather and water: mapping Escherichia coli O157:H7 infections in humans in England and Scotland
Money, P., Kelly, A.F., Gould, S.W.J, Denholm-Price, J., Threlfall, E.J. and Fielder, M., 2010, Environmental Microbiology (12), 10, pp 2633-2644
The need for continued monitoring of antibiotic resistance patterns in clinical isolates of Staphylococcus aureus from London and Malta
Gould, Simon WJ, Cuschieri, Paul, Rollason, Jess, Hilton, Anthony C, Easmon, Sue and Fielder, Mark D, 2010, Annals of Clinical Microbiology and Antimicrobials (9), 20
Hepatitis C virus prevalence and serotypes associated with HIV in The Gambia
Mboto, C. I., Fielder, M., Davies-Russell, Angela and Jewell, A., 2010, British Journal of Biomedical Science (67), 3, pp 140-144
Biochemical and genetic variation in Mycoplasma fermentans strains from cell line, human and animal sources
Afshar, B., Nicholas, R.A.J., Pitcher, D., Fielder, M.D. and Miles, R.J., 2009, Journal Of Applied Microbiology (107), 2, pp 498-505
The evaluation of novel chromogenic substrates for the detection of lipolytic activity in clinical isolates of Staphylococcus aureus and MRSA from two European study groups
Gould, Simon W J, Chadwick, Maureen, Cuschieri, Paul, Easmon, Susan, Richardson, Anthony C, Price, Robert G and Fielder, Mark D, 2009, FEMS Microbiology Letters (297), 1, pp 10-16
Anti-microbial activities of pomegranate rind extracts: enhancement by cupric sulphate against clinical isolates of S. aureus, MRSA and PVL positive CA-MSSA
Gould, Simon WJ, Fielder, Mark D, Kelly, Alison F and Naughton, Declan P, 2009, BMC Complementary and Alternative Medicine (9), 23
An alternative methodology for the prediction of adherence to anti HIV treatment
Thompson, Richard, Bidgood, Penelope, Petroczi, Andrea, Denholm-Price, James C.W. and Fielder, Mark D., 2009, AIDS Research and Therapy (6), 9
The antimicrobial properties of copper surfaces against a range of important nosocomial pathogens
Gould, Simon W. J., Fielder, Mark D., Kelly, Alison F., Morgan, Marina, Kenny, Jackie and Naughton, Declan P., 2009, Annals of Microbiology (59), 1, pp 151-156
Prevalence of HIV-1, HIV-2, hepatitis C and co-infection in The Gambia
Mboto, C.I., Fielder, Mark, Davies-Russell, Angela and JEWELL, ANDREW, 2009, West African Journal of Medicine (28), 1, pp 306-309
Antimicrobial pomegranate rind extracts: enhancement by Cu(II) and vitamin C combinations against clinical isolates of Pseudomonas aeruginosa
Gould, S W J, Fielder, M D, Kelly, A F, El Sankary, W and Naughton, D P, 2009, British Journal of Biomedical Science (66), 3, pp 129-132
CD4+ lymphocyte values and trends in individuals infected with Human Immunodeficiency Virus and/or co-infected with Hepatitis C virus in The Gambia
Mboto, CI, Davies-Russell, A, Fielder, M and Jewell, A P, 2009, African Health Sciences (9), 3, pp 130-136
Antimicrobial activities of pomegranate rind extracts: enhancement by addition of metal salts and vitamin C
McCarrell, Erin M, Gould, Simon WJ, Fielder, Mark D, Kelly, Alison F, El Sankary, Waffa and Naughton, Declan P, 2008, BMC Complementary and Alternative Medicine (8), 64, pp 1-7
UK epidemic strains of meticillin-resistant Staphylococcus aureus in clinical samples from Malta
Gould, Simon W J, Rollason, Jess, Hilton, Anthony C, Cuschieri, Paul, McAuliffe, Laura, Easmon, Susan L and Fielder, Mark D, 2008, Journal of Medical Microbiology (57), 11, pp 1394-1398
The withdrawal of antimicrobial treatment as a mechanism for defeating resistant microorganisms
Stokes, David J., Kelly, Alison F., Gould, Simon W. J., Cassar, Claire A. and Fielder, Mark D., 2008, (53), 3, pp 300-305
A novel medium devoid of ruminant peptone for high yield growth of Mycoplasma ovipneumoniae
Patel, Hiren, Mackintosh, David, Ayling, Roger D., Nicholas, Robin A. J. and Fielder, Mark D., 2008, Veterinary Microbiology (127), 3-4, pp 309-314
Statistical analysis of HIV-patient data from central Europe: lessons from a three-centre study
Thompson, R.I., Bidgood, P., Petroczi, A., Denholm-Price, J. and Fielder, M., 2008, European Infectious Disease (2), 1, pp 52-56
Induction of oxidative DNA damage by Helicobacter pylori in HT29 cells
Coffils, M., Jewell, A.P., Jones, L.A. and Fielder, M.D., 2007, British Journal of Biomedical Science (64), 4, pp 149-152
Human immunodeficiency virus and hepatitis C co-infection in sub-Saharan West Africa
Mboto, C.I., Davies, A., Fielder, M. and Jewell, A.P., 2006, British Journal of Biomedical Science (63), 1, pp 29-37
Biochemical characterisation of some non fermenting, non arginine hydrolysing mycoplasmas of ruminants
Khan, Liaqat Ali, Loria, Guido R., Ramirez, Anna Sofia, Nicholas, Robin A.J., Miles, Roger J. and Fielder, Mark D., 2005, Veterinary Microbiology (109), 1-2, pp 129-134
Hepatitis C antibodies in asymptomatic first-time blood donors in The Gambia: prevalence and risk factors
Mboto, C.I., Davies-Russell, A., Fielder, M. and Jewell, A.P., 2005, British Journal of Biomedical Science (62), 2, pp 89-91
Vaccination against bacterial gut infections
Fielder, M and Lewis, D J M, 1998, Current Opinion in Infectious Diseases (11), 5, pp 591-596
Antibodies to Klebsiella pneumoniae in Dutch patients with ankylosing spondylitis and acute anterior uveitis and to Proteus mirabilis in rheumatoid arthritis
Blankenberg-Sprenkels, S H, Fielder, M, Feltkamp, T E, Tiwana, H, Wilson, C and Ebringer, A, 1998, Journal of Rheumatology (25), 4, pp 743-747
Antibodies to Klebsiella, Proteus, and HLA-B27 peptides in Japanese patients with ankylosing spondylitis and rheumatoid arthritis
Tani, Y, Tiwana, H, Hukuda, S, Nishioka, J, Fielder, M, Wilson, C, Bansal, S and Ebringer, A, 1997, Journal of Rheumatology (24), 1, pp 109-114
Molecular mimicry: the geographical distribution of immune responses to Klebsiella in ankylosing spondylitis and its relevance to therapy
Ebringer, A, Ahmadi, K, Fielder, M, Rashid, T, Tiwana, H, Wilson, C, Collado, A and Tani, Y, 1996, Clinical Rheumatology (15), Suppleme, pp 57-61
Nipah virus ecology and infection dynamics in its bat reservoir, 'Pteropus medius', in Bangladesh
Epstein, J.H., Anthony, S.J., Islam, A., Kilpatrick, A.M., Khan, S. Ali, Ross, N., Smith, I., Barr, J., Zambrana-Torrelio, C., Tao, Y., Islam, A., Quan, P.L., Olival, K., Gurley, E., Hossain, M.J., Field, H.E., Fielder, M., Briese, T., Rahman, M., Crameri, G., Wang, L.-F., Luby, S., Lipkin, W.I. and Daszak, P.(2016). In: International Meeting on Emerging Diseases and Surveillance (IMED) 2016, 04-07 Nov 2016 :Vienna, Austria
Antihypertensive and antibacterial investigations of novel nitric oxide donor compounds.
Hills, Daniel, Mohseni, Maria, Dowler, Jan, Greenwood, Iain, Fielder, Mark, Pearson, Russell and Perumal, Dhaya(2014). In: 8th International conference on the biology, chemistry and therapetic application of Nitric Oxide, 16-20 June, 2014 :Cleveland, Ohio, U.S.A.
Roles for DNA repeats in 'Neisseria gonorrhoeae', including protein sequence variation
Spencer-Smith, R., Nebel, J.-C., Norman, B., Zelewska, M., Bharaj, D., Fielder, M. and Snyder, L.(2012). In: XVIIIth International Pathogenic Neisseria Conference (IPNC), 09 - 14 Sep 2012 :Würzburg, Germany
Sequence features contributing to chromosomal rearrangements in 'Neisseria gonorrhoeae'
Spencer-Smith, R., Varkey, E., Fielder, M. and Snyder, L.(2012). In: XVIIIth International Pathogenic Neisseria Conference (IPNC), 09 - 14 Sep 2012 :Würzburg, Germany
Predicting Response to Antiretroviral Treatments in HIV Patients - the EuResist Project
Bidgood, Penelope, Denholm-Price, James, Fielder, Mark, Petróczi, Andrea and Thompson, Richard(2007). In: Statistics in Public Policy-Making: Hope vs. Reality, 16 -20 Jul 2007 :York, U.K.