Nano-composite materials are gaining prominence in a multitude of scientific areas including medicine, catalysis, optics, photonics and energy, to name a few, as nanotechnology continues to play a critical role in shaping the future of scientific and technological developments in the 21st century. This PhD project will look at integrating nanomaterials into hydrogel matrices for both environmental and bioremedial purposes. Material synthesis will focus on developing methods that are low-cost, energy-efficient and with potential for scale-up. Modes of delivery will explore pathways that are sustainable, robust and with minimal environmental impact for the water purification application; and non-invasive, biocompatible and safe for the drug delivery application.
I completed my undergraduate studies at Kingston university London (MChem in Chemistry) in 2019 with a 2:1. I completed my master's dissertation under Dr Ayomi Perera, in which I developed magnetic cryogel composite materials for thermally triggered drug delivery. I also participated in a summer research internship scheme under the supervision of Dr Stephen Wren(summer of 2018), developing squaric acid building blocks that enable bioisosteric replacement of carboxylic acids.
My research focuses on the development of nanocomposite materials for use in environmental and medical uses, with specific attention on the development of titanosilicate materials for organic water pollutant degradation and continuing to create and optimize iron oxide cryogel composites for use in drug delivery.
Bristow, R. M. D.; Foot, P. J. S.; McGettrick, J. D.; Bear, J. C.; Perera, A. S. Sustainable Synthesis of Titanium Based Photocatalysts via Surfactant Templating: From Kerosene to Sunflower Oil. Mater Adv 2024, Advance Article. https://doi.org/10.1039/D3MA00957B.
Perera, A. S.; Jackson, R. J.; Bristow, R. M. D.; White, C. A. Magnetic Cryogels as a Shape-Selective and Customizable Platform for Hyperthermia-Mediated Drug Delivery. Sci Rep 2022, 12 (1), 9654. https://doi.org/10.1038/s41598-022-13572-9.
Perera, A. S.; Melia, P. M.; Bristow, R. M. D.; McGettrick, J. D.; Singer, R. J.; Bear, J. C.; Busquets, R. A Non-Doped Microporous Titanosilicate for Bimodal Adsorption-Photocatalysis Based Removal of Organic Water Pollutants. Microporous and Mesoporous Materials 2022, 345, 112276. https://doi.org/10.1016/j.micromeso.2022.112276.
Bossmann, S.H.; Payne, M.M.; Kalita, M.; Bristow, R.M.D.; Afshar, A.; Perera, A.S. Iron-Based Magnetic Nanosystems for Diagnostic Imaging and Drug Delivery: Towards Transformative Biomedical Applications. Pharmaceutics 2022, 14, 2093. https://doi.org/10.3390/pharmaceutics14102093