Professor Fawaz Aldabbagh
Faculties, deparments and locations
- Faculty of Health, Science, Social Care and Education
- Department of Pharmacy
- School of Life Sciences, Pharmacy and Chemistry
- Penrhyn Road
Chair of Medicinal / Pharmaceutical Chemistry
- Email:
- f.aldabbagh@kingston.ac.uk
About
I have nearly 25 years' experience as a principal investigator (PI) and more than 100 peer-reviewed research publications. My group has an international reputation for excellence in synthetic organic and polymer chemistry, with applications in drug discovery and materials science. As PI, I have supervised 28 PhDs to completion, and directed the research of postdoctoral workers. I joined Kingston University in September 2017, after 17.5 years at the National University of Ireland Galway (NUI Galway, now University of Galway).
At NUI Galway, I was Lecturer, then Senior Lecturer in Chemistry, and for a time, Vice Dean for the College of Science (Research). In 2007, I was Canon Foundation Research Fellow at Kobe University in Japan, and I have held Visiting Professorships at the Universities of Reims Champagne-Ardenne and Le Havre (France) in 2013 and 2014. I am Fellow of the Royal Society of Chemistry (FRSC, UK) since 2009.
I was section Editor for Comprehensive Heterocyclic Chemistry IV (Elsevier, published in 2022). I serve on the Editorial Board of Molecules (Basel, MDPI) and I am Editor-in-Chief for Molbank (Basel, MDPI). I was Adjunct Professor at NUI Galway (2017-2020). I was chair of the organizing committee for Bioheterocycles 2017 (International Conference on Heterocycles in Bioorganic Chemistry) held in Galway and RSC Organic London & SE Division Meeting at Kingston University in 2020.
Qualifications
- BSc (Hons), Brunel University
- PhD, Loughborough University
- FRSC
- FHEA, Kingston University
Domains
Specialisms
- Organic Chemistry
- Polymer Chemistry
- Medicinal Chemistry and Cancer Research
Scholarly affiliations
- Adjunct Professor at NUI Galway
- Section Editor for Comprehensive Heterocyclic Chemistry IV (Elsevier)
- Editor of Molecules (Basel, MDPI)
- Editor-in-Chief of Molbank (Organic Synthesis Section, Basel, MDPI)
- Arkivoc Editorial Board of Referees
- EPSRC Peer Review College
Publications
Stimuli-responsive nanoparticles from RAFT dispersion polymerization-induced self-assembly (PISA) of N-phenylacrylamide copolymerized with a boronic acid-substituted derivative
Aldabbagh, Fawaz, Ishizuka, Fumi, Kerdi, Youssef, Balouchi, Morvarid H., Dhiraj, Harpal S. and Zetterlund, Per B., 2024, European Polymer Journal (220), pp 113488
Nucleoside analogues for chagas disease and leishmaniasis therapy : current status and future perspectives
Nwoke, Emmanuel Awucha, Lowe, Silvester, Aldabbagh, Fawaz, Kalesh, Karunakaran and Kadri, Hachemi, 2024, Molecules (29), 22, pp 5234
1-(2,5-Dimethoxy-4-nitrophenyl)piperidine
Syeda, Tanjia M., Al-Shaidi, Muadh R., Basri, Ibtihal, Merzouk, Mahboub and AlDabbagh, Fawaz, 2023, Molbank (2023), 4, pp M1744
Heterocyclic iminoquinones and quinones from the National Cancer Institute (NCI, USA) COMPARE analysis
Haji, Naemah, Faizi, Masoma, Koutentis, Panayiotis A., Carty, Michael P. and Aldabbagh, Fawaz, 2023, Molecules (28), 13, pp 5202
Lactate and glucose induced self‐assembly of hydrophobic boronic acid‐substituted polymers
Dhiraj, Harpal S., Ishizuka, Fumi, Elshaer, Amr, Zetterlund, Per B. and Aldabbagh, Fawaz, 2023, Journal of Polymer Science
Lactate and glucose responsive boronic acid-substituted amphiphilic block copolymer nanoparticles of high aspect ratio
Dhiraj, Harpal S., Ishizuka, Fumi, Saeed, Maria, Elshaer, Amr, Zetterlund, Per B. and Aldabbagh, Fawaz, 2023, European Polymer Journal, pp 111819
RAFT dispersion polymerization induced self-assembly (PISA) of boronic acid-substituted acrylamides
Dhiraj, Harpal S., Ishizuka, Fumi, Elshaer, Amr, Zetterlund, Per B. and Aldabbagh, Fawaz, 2022, Polymer Chemistry (13), 25, pp 3750-3755
CF₃-Bis-TEMPO-Vis : new visible light active bis-benzimidazolequinone alkoxyamine
Kielty, Patrick, Farràs, Pau, Smith, Dennis A. and Aldabbagh, Fawaz, 2021, Molbank (2021), 4, pp M1300
Visible light activated benzimidazolequinone alkoxyamines of 1,1,3,3‐tetramethylisoindolin‐2‐yloxyl (TMIO)
Kielty, Patrick, Chalmers, Benjamin A., Farràs, Pau, Smith, Dennis A. and Aldabbagh, Fawaz, 2021, European Journal of Organic Chemistry (2021), 48, pp 6652-6657
Advances in the synthesis of ring-fused benzimidazoles and imidazobenzimidazoles
Sweeney, Martin, Conboy, Darren, Mirallai, Styliana I. and Aldabbagh, Fawaz, 2021, Molecules (26), 9, pp 2684
Ring-fused dimethoxybenzimidazole-benzimidazolequinone (DMBBQ) : tunable halogenation and quinone formation using NaX/Oxone
Conboy, Darren, Kielty, Patrick, Bear, Joseph C., Cockcroft, Jeremy K., Farràs, Pau, McArdle, Patrick, Singer, Richard J., Smith, Dennis A. and Aldabbagh, Fawaz, 2021, (12), pp 2716-2724
Correction: Visible-light unmasking of heterocyclic quinone methide radicals from alkoxyamines
Kielty, Patrick, Farràs, Pau, McArdle, Patrick, Smith, Dennis A. and Aldabbagh, Fawaz, 2020, Chemical Communications, 79, pp 11891
2-(Fluoromethyl)-4,7-dimethoxy-1-methyl-1H -benzimidazole
Kielty, Patrick, Farràs, Pau, Smith, Dennis A. and Aldabbagh, Fawaz, 2020, Molbank (2020), 2, pp M1129
6-Imino-1,2,3,4,8,9,10,11-octahydropyrido[1,2- a ]pyrido[1′,2′:1,2]imidazo[4,5- f ]benzimidazole-13-one : synthesis and cytotoxicity evaluation
Conboy, Darren and Aldabbagh, Fawaz, 2020, Molbank (2020), 1, pp M1118
The reactivity of Oxone towards 4,6-di(cycloamino)-1,3-phenylenediamines : synthesis of spirocyclic oxetane ring-fused imidazobenzimidazoles
Conboy, Darren and Al-Dabbagh, Fawaz, 2020, Arkivoc (2020), vii, pp 180-191
Visible-light unmasking of heterocyclic quinone methide radicals from alkoxyamines
Kielty, Patrick, Farras, Pau, McArdle, Patrick, Smith, Dennis A. and Aldabbagh, Fawaz, 2019, Chemical Communications (55), 97, pp 14665-14668
Incorporating morpholine and oxetane into benzimidazolequinone anti-tumor agents : the discovery of 1,4,6,9-tetramethoxyphenazine from hydrogen peroxide and hydroiodic acid-mediated oxidative cyclizations
Conboy, Darren, Mirallai, Styliana I., Craig, Austin, McArdle, Patrick, Al-Kinani, Ali A., Barton, Stephen and Aldabbagh, Fawaz, 2019, The Journal of Organic Chemistry (84), 15, pp 9811-9818
Polymerization-induced self-assembly based on ATRP in supercritical carbon dioxide
Alzahrani, Abdullah, Zhou, Dewen, Kuchel, Rhiannon P., Zetterlund, Per B. and Aldabbagh, Fawaz, 2019, Polymer Chemistry (10), 21, pp 2658-2665
Regioselective fluorination of 7-oxo-1,2,4-benzotriazines using selectfluor
Mirallai, Styliana I., Koutentis, Panayiotis A. and Aldabbagh, Fawaz, 2019, Molecules (24), 2, pp 282
One-pot synthesis of dihalogenated ring-fused benzimidazolequinones from 3,6-Dimethoxy-2-(cycloamino)anilines using hydrogen peroxide and hydrohalic acid
Sweeney, Martin, Keane, Lee-Ann J., Gurry, Michael, McArdle, Patrick and Al-Dabbagh, Fawaz, 2018, Organic Letters (20), 21, pp 6970-6974
Radical polymerization of alkyl 2-cyanoacrylates
Duffy, Cormac, Zetterlund, Per B. and Aldabbagh, Fawaz, 2018, Molecules (23), 2, pp 465
Synthesis of N-[(dialkylamino)methyl)]acrylamides and N-[(dialkylamino)methyl]methacrylamides from Schiff base salts : useful building blocks for smart polymers
Alzahrani, Abdullah, Mirallai, Styliana I., Chalmers, Benjamin A., McArdle, Patrick and Aldabbagh, Fawaz, 2018, (22), pp 4108-4116
Selective methylmagnesium chloride mediated acetylations of isosorbide : a route to powerful nitric oxide donor furoxans
Kielty, Patrick, Smith, Dennis A., Cannon, Peter, Carty, Michael P., Kennedy, Michael, McArdle, Patrick, Singer, Richard J. and Aldabbagh, Fawaz, 2018, Organic Letters (20), 10, pp 3025-3029
Anti-cancer activity of phenyl and pyrid-2-yl 1,3-substituted benzo[1,2,4]triazin-7-ones and stable free radical precursors
Keane, Lee-Ann J., Mirallai, Styliana I., Sweeney, Martin, Carty, Michael P., Zissimou, Georgia A., Berezin, Andrey A., Koutentis, Panayiotis A. and Aldabbagh, Fawaz, 2018, Molecules (23), 3, pp 574
1-Fluoro-2,5-dimethoxy-4-nitrobenzene
Sweeney, Martin, McArdle, Patrick and Aldabbagh, Fawaz, 2018, Molbank (2018), 1, pp M984
CO[sub]2-responsive polyacrylamide copolymer vesicles with acid-sensitive morpholine moieties and large hydrophobic RAFT end-group
Chalmers, Benjamin A., Magee, Christopher, Cheung, David L., Zetterlund, Per B. and Al-Dabbagh, Fawaz, 2017, European Polymer Journal (97), pp 129-137
Greener synthesis using hydrogen peroxide in ethyl acetate of alicyclic ring-fused benzimidazoles and anti-tumour benzimidazolequinones
Sweeney, Martin, Gurry, Michael, Keane, Lee-Ann J. and Aldabbagh, Fawaz, 2017, Tetrahedron Letters (58), 36, pp 3565-3567
Efficient synthesis and RAFT polymerization of the previously elusive N -[(cycloalkylamino)methyl]acrylamide monomer class
Chalmers, Benjamin A., Alzahrani, Abdullah, Hawkins, Gerard and Aldabbagh, Fawaz, 2017, Journal of Polymer Science Part A: Polymer Chemistry (55), 13, pp 2123-2128
Reversible addition-fragmentation chain transfer polymerization of alkyl-2-cyanoacrylates : an assessment of livingness
Duffy, Cormac, Phelan, Marisa, Zetterlund, Per B. and Aldabbagh, Fawaz, 2017, Journal of Polymer Science Part A: Polymer Chemistry (55), 8, pp 1397-1408
Effects of material thickness and processing method on poly(lactic-co-glycolic acid) degradation and mechanical performance
Shirazi, Reyhaneh Neghabat, Aldabbagh, Fawaz, Ronan, William, Erxleben, Andrea, Rochev, Yury and McHugh, Peter, 2016, Journal of Materials Science: Materials in Medicine (27), 154
Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones : very strong correlation to pleurotin and thioredoxin reductase inhibition
Sweeney, Martin, Coyle, Robert, Kavanagh, Paul, Berezin, Andrey A., Lo Re, Daniele, Zissimou, Georgia A., Koutentis, Panayiotis A., Carty, Michael P. and Aldabbagh, Fawaz, 2016, (24), 16, pp 3565-3570
A new era for homolytic aromatic substitution : replacing Bu[sub]3SnH with efficient light-induced chain reactions
Gurry, Michael and Aldabbagh, Fawaz, 2016, (14), 16, pp 3849-3862
Synthesis of a Spirocyclic Oxetane-Fused Benzimidazole
Gurry, Michael, McArdle, Patrick and Al-Dabbagh, Fawaz, 2015, Molecules (20), 8, pp 13864-13874
One-pot hydrogen peroxide and hydrohalic acid induced ring closure and selective aromatic halogenation to give new ring-fused benzimidazoles
Gurry, Michael, Sweeney, Martin, McArdle, Patrick and Aldabbagh, Fawaz, 2015, Organic Letters (17), 11, pp 2856-2859
RAFT polymerization in supercritical carbon dioxide based on an induced precipitation approach : synthesis of 2-ethoxyethyl methacrylate/acrylamide block copolymers
Hawkins, Gerard, Zetterlund, Per B and Aldabbagh, Fawaz, 2015, Journal of Polymer Science Part A : Polymer Chemistry (53), 20, pp 2351-2356
Nanomechanical properties of poly(lactic-co-glycolic) acid film during degradation
Shirazi, Reyhaneh Neghabat, Aldabbagh, Fawaz, Erxleben, Andrea, Rochev, Yury and McHugh, Peter, 2014, Acta Biomaterialia (10), 11, pp 4695-4703
Photochemical aryl radical cyclizations to give (E)-3-Ylideneoxindoles
Gurry, Michael, Allart-Simon, Ingrid, McArdle, Patrick, Gerard, Stephane, Sapi, Janos and Aldabbagh, Fawaz, 2014, Molecules (19), 10, pp 15891-15899
Synthesis of fluorinated alkoxyamines and alkoxyamine-initiated nitroxide-mediated precipitation polymerizations of styrene in supercritical carbon dioxide
Magee, Christopher, Earla, Aruna, Petraitis, Jennifer, Higa, Chad, Braslau, Rebecca, Zetterlund, Per B and Aldabbagh, Fawaz, 2014, Polymer Chemistry (5), pp 5725-5733
Tandem reactions via Barton esters with intermolecular addition and vinyl radical substitution onto indole
Coyle, Robert, McArdle, Patrick and Aldabbagh, Fawaz, 2014, The Journal of Organic Chemistry (79), 12, pp 5903-5907
Chain transfer to solvent in the radical polymerization of structurally diverse acrylamide monomers using straight-chain and branched alcohols as solvents
Magee, Christopher, Sugihara, Yusuke, Zetterlund, Per B and Aldabbagh, Fawaz, 2014, Polymer Chemistry (5), 7, pp 2259-2265
A thermally activated drug delivery system based on a thermoresponsive polymer and a cooling device : a theoretical assessment
Vo, Tuoi T. N., Yang, Rongbing, Aldabbagh, Fawaz, Carroll, William, Meere, Martin and Rochev, Yury, 2014, Journal of Thermal Science and Engineering Applications (6), 2, pp 21012
Bicyclic 5-5 systems : two heteroatoms 1:1
Kielty, Patrick and Aldabbagh, Fawaz (2022). In: Aldabbagh, Fawaz, (ed.), Comprehensive Heterocyclic Chemistry IV. Amsterdam: Elsevier, pp 1-40
Tricyclic systems : central carbocyclic ring with fused five-membered rings
Conboy, Darren and Aldabbagh, Fawaz (2022). In: Aldabbagh, Fawaz, (ed.), Comprehensive Heterocyclic Chemistry IV. Amsterdam: Elsevier, pp 943-1002