Mrs Zainab Al-Jeboory
Contact
- Email: k2029915@kingston.ac.uk
- Location: Penrhyn Road
- Faculty: Faculty of Engineering, Computing and the Environment
- School: School of Life Sciences, Pharmacy and Chemistry
- Department: Department of Biomolecular Sciences
Research project: Molecular mechanisms of multidrug resistance in Neisseria gonorrhoeae
Abstract
A doctorate research project that investigates Neisseria gonorrhoeae, the Gram-negative bacteria, and the molecular mechanisms involved in this bacteria's multidrug resistance. The research objectives include investigating the genes and mutations involved, as well as the transcriptional control of these determinants. Since the 1970s, there has been an increase of antimicrobial resistance (AMR) in Neisseria gonorrhoeae which has been greatly compromising the management and control of the disease. The last-line treatment for gonorrhoea, extended-spectrum cephalosporins (ESCs), have been reported to have decreased effectiveness in treating gonorrhoea globally. International collaborative efforts remain vital to control the disease and improve prevention, as well as early diagnosis. The advent of rapid and inexpensive whole-genome sequencing can be utilised to help find genetic mutations that confer multidrug resistance in bacterial cells. This data can provide insight to guide attempts to find suitable treatment plans and more personalised medication approaches based on specific bacterial strains.
- Research degree: PhD
- Title of project: Molecular mechanisms of multidrug resistance in Neisseria gonorrhoeae
- Research supervisor: Professor Lori Snyder
- Other research supervisors:
Biography
I graduated from King's College London with a degree in Biomedical Science with an in-depth look into genetics during my final year. I was then awarded Kings Undergraduate Research Fellowship which allowed me to experience statistical analysis for Genetic Data in the Twins UK research department. After finalising the internship, I was employed by the department as a clinical research assistant whereby I conducted tests on clinical trial participants.
A year on, I began a Genomic Medicine MSc at Queen Mary's University of London, which I completed with a Merit and Distinction in my thesis.
At the moment, I am conducting my PhD research in which I am investigating the molecular mechanisms of multidrug resistance in Neisseria gonorrhoeae, under the supervision of Professor Lori Snyder.
I aspire to further enhance my research and teaching skills with further career progression.
Areas of research interest
- Genomics
- Neisseria Gonorrhea
- Microbiology
- Antibiotic Resistance
- Pharmacology
Qualifications
- MSc Genomic Medicine, Queen Mary's University of London
- BSc Biomedical Science, King's College London
Funding or awards received
- PhD Starter Bursary