Mr Muadh Al-Shaidi

Research project: Synthesis of Bis-Benzimidazolequinone Anti-Cancer Agents via DiMethoxyBenzimidazoleBenzimidazoleQuinone (DMBBQ)

Abstract

Over the past 20 years, the research group of Professor Fawaz Aldabbagh at Kingston University (previously at University of Galway) have reported several heterocyclic iminoquinone and quinone alternatives to the clinically used anti-cancer drug mitomycin C (marketed as Mutamycin). In this drug discovery project, we aim to prepare and evaluate the activity of a new class of novel anti-cancer agents, namely bis-benzimidazolequinones. These will be prepared via DMBBQ using novel synthetic methods.

  • Research degree: PhD
  • Title of project: Synthesis of Bis-Benzimidazolequinone Anti-Cancer Agents via DiMethoxyBenzimidazoleBenzimidazoleQuinone (DMBBQ)
  • Research supervisor: Professor Fawaz Aldabbagh
  • Other research supervisor: Dr Stephen Barton

Biography

I am a native of Oman. I completed BSc in Chemistry in 2022 from Sultan Qaboos University and MSc in Analytical Chemistry (Distinction) at Kingston University in 2024. I have published work from my BSc project on extraction of antioxidants from Omani honey. I also published work in Molbank during my MSc project with Prof. Aldabbagh, and I am now continuing my research career with a PhD under his direction at Kingston University.

Areas of research interest

  • Organic Synthesis
  • Cancer
  • Pharmaceutical Science
  • Heterocyclic Chemistry
  • Drug Discovery

Qualifications

  • BSc in Chemistry, Sultan Qaboos University
  • MSc in Analytical Chemistry (Distinction), Kingston University

Publications

1-(2,5-Dimethoxy-4-nitrophenyl)piperidine, Tanjia M. Syeda, Muadh R. Al-Shaidi, Ibtihal Basri, Mahboub Merzouk and Fawaz Aldabbagh, Molbank (Basel MDPI) 2023, 2023, M1744. https://doi.org/10.3390/M1744