Cannabinoids, particularly THC and its metabolites, are among the most commonly used drugs of abuse in the UK. Despite their widespread use, the long-term effects of cannabinoids on major organs, particularly the heart, remain poorly understood. While substances like alcohol (ethanol) are known to induce fibrosis and structural changes in cardiac and hepatic tissues, the impact of cannabinoids on these organs has been less conclusive. My research investigates the cellular and molecular mechanisms by which cannabinoids, particularly THC-OH and THC-COOH, contribute to the development of cardiac fibrosis. Through exploring the PI3K/AKT signalling pathway and its role in cytoskeletal dynamics and extracellular matrix remodelling, this project aims to elucidate the potential cardiovascular risks posed by chronic cannabis use and identify molecular targets for future therapeutic interventions.
I hold a PhD in Molecular Biology and Forensic Toxicology from Kingston University, with a research focus on the cardiovascular impacts of cannabinoids. Over the course of my career, I have developed extensive laboratory and research expertise, contributing to three peer-reviewed publications. My academic journey, including a BSc (Hons) and MSc in Forensic Medical Sciences, has provided me with a strong foundation in molecular biology, toxicology, and cell biology. I am enthusiastic about collaborating on projects in the medical and pharmaceutical sectors and am committed to advancing research in forensic toxicology, cardiovascular health, and molecular mechanisms. Through both academic and industry-focused initiatives, I aim to contribute to impactful advancements in science and medicine.