Inflammation is the body's response of the immune system to a number of a different factors. At the tissue level, inflammation is characterised by redness, swelling, heat and pain. There are a number of different inflammatory conditions of the ocular surface that require treatment, and researchers are looking into novel approaches to treat these eye diseases. Currently over 90% of ophthalmic drugs are administered in the form of eye drops. Eye drops offer very poor bioavailability of ~5% so new methods of treatment are needed. Ocular in situ gelling inserts could be used as a new method of administering ophthalmic drugs while improving the stability and bioavailability of the drug. I will be testing for inflammation of the ocular surface and potential novel drug delivery methods for the administration of Tacrolimus; a drug that isn't widely used for ophthalmic purposes.
A BSc Pharmaceutical Science graduate with extensive experience in laboratory work. A highly self-motivated and determined individual who is able to work effectively and efficiently in a group or as an individual. I have had considerable experience working in formulation and have gained a number of competence badges throughout my studies, demonstrating my ability to work safely and effectively in the lab and use instrumentation successfully.Currently undertaking a PhD titled: Inflammatory conditions of the ocular surface: Formulation and drug delivery as potential treatment for management